_:b701992 . _:b701989 . _:b701993 . _:b701991 . _:b780226 . "Pappalysin-1"^^ . "176385"^^ . . "EC 3.4.24.79SYNCI" . _:b701993 . "Q13219"^^ . "NICHD"^^ . _:b780225 _:b780226 . "IGF-Dependent IGFBP-4 ProteaseSYNCI" . _:b701993 . _:b780224 _:b780225 . "Low plasma levels of pappalysin-1 during pregnancy may be a biomarker of an aneuploid fetus."^^ . "PAPP-ASYNCI" . _:b701992 . _:b780224 _:b701990 . _:b701990 . . _:b701989 . _:b636903 _:b733126 . _:b701987 . _:b701993 . _:b780225 _:b701991 . "NCIPappalysin-1 (1627 aa, ~181 kDa) is encoded by the human PAPPA gene. This protein is involved in the modulation of proteolysis." . _:b780226 _:b701992 . _:b636903 . "IGFBP-4aseSYNCI" . _:b701988 . "Pregnancy-Associated Plasma Protein ASYNCI" . _:b780222 _:b780223 . "Pappalysin-1"^^ . _:b733126 . _:b701990 . _:b701990 . _:b701992 . _:b701991 . _:b701987 . _:b701991 . "Insulin-Like Growth Factor-Dependent IGF-Binding Protein 4 ProteaseSYNCI" . "Pregnancy Associated Plasma Protein APTNICHD" . _:b780221 _:b780222 . _:b780222 _:b701988 . _:b701988 . "Pappalysin-1PTNCI" . "Pappalysin-1 specifically cleaves IGFBP-4 between 143-Ser and Lys-144 and IGFBP-5 between 135-Met and Lys-136. (UniProt)"^^ . _:b636903 . _:b701989 . "C2984583"^^ . _:b780223 _:b701989 . _:b701988 . _:b701987 . _:b780221 _:b701987 . "Amino Acid, Peptide, or Protein"^^ . . . . _:b780223 _:b780224 . "C91825"^^ . _:b733126 _:b780221 .