"FDA"^^ . "176P5C4QU8"^^ . "C11H18N2O5"^^ . "Pharmacologic Substance"^^ . . "IdraprilPTNCI" . "Idrapril"^^ . "C0172867"^^ . "Idrapril"^^ . . "A hydroxamic, non-amino acid derivative angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Idrapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI" . . "C83780"^^ . "IDRAPRILPTFDA176P5C4QU8" . . "127420-24-0"^^ .