_:b643581 . "Abciximab"^^ . "C76128"^^ . . "Chimeric 7E3 FabSYNCI" . . "ReoProBRNCI" . "AbciximabPTNCI" . . . "C0288672"^^ . "143653-53-6"^^ . _:b643581 . "as an adjunct to aspirin and heparin for the prevention of acute cardiac ischemic complications"^^ . _:b643581 . "FDA"^^ . "MoAb 7E3ABNCI" . "Amino Acid, Peptide, or Protein"^^ . . . "Immunologic Factor"^^ . "X85G7936GV"^^ . "Abciximab"^^ . "A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation.NCI" . "Abciximab"^^ . _:b643581 . "ABCIXIMABPTFDAX85G7936GV" .