"1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthroquinone DihydrochlorideSNNCI" . "DHAQABNCI" . "Acute Leukemia; Breast cancer; Non Hodgkins Lymphoma; Multiple sclerosis; Prostate cancer"^^ . "Dihydroxyanthracenedione DihydrochlorideSYNCI" . "Mitoxantrone HydrochloridePTNCI" . . "Mitoxantrone Hydrochloride"^^ . "CHEBI:50727"^^ . "Organic Chemical"^^ . "C665"^^ . "C1513359"^^ . "The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.NCI" . "301739"^^ . "FDA"^^ . "39219"^^ . "Antibiotic"^^ . "A drug used to treat advanced prostate cancer that does not respond to hormones, adult acute nonlymphocytic leukemia, and advanced or chronic multiple sclerosis. It is also being studied in the treatment of other cancers. It belongs to the family of drugs called antitumor antibiotics.NCI-GLOSS" . "C22H28N4O6.2HCl"^^ . "PralifanFBNCI" . . . "NovantroneBRNCI" . "OnkotroneFBNCI" . "Mitoxantrone"^^ . "MitroxoneFBNCI" . "DHADABNCI" . "1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione DihydrochlorideSNNCI" . "MITOXANTRONE HYDROCHLORIDEPTFDAU6USW86RD0" . "DHAQSYDTPNSC0279836" . . . "39219"^^ . "NovantronePTNCI-GLOSSCDR0000413952" . "Mitozantrone HydrochlorideSYNCI" . "Mitoxantrone DihydrochlorideSYNCI" . "Acute leukemia; Adult lymphoblastic lymphoma; AIDS-Related lymphoma; Breast cancer; Chronic myelogenous leukemia; Hodgkins lymphoma; Lymphoblastic lymphoma; Myelodysplastic syndrome; Ovarian epithelial cancer; Prostate cancer"^^ . "70476-82-3"^^ . "Mitoxantroni HydrochloridumSYNCI" . "Mitoxantrone Hydrochloride"^^ . . "DHADSYDTPNSC0301739" . "CL 232315CNNCI" . "NeotalemFBNCI" . "U6USW86RD0"^^ .