"FDA"^^ . "Propiomazine_Hydrochloride"^^ . "CHEBI:8492"^^ . . "C20H24N2OS.HCl"^^ . . . "Propiomazine Hydrochloride"^^ . . "Propiomazine Hydrochloride"^^ . "Pharmacologic Substance"^^ . "1240-15-9"^^ . "Propiomazine HydrochloridePTNCI" . "PROPIOMAZINE HYDROCHLORIDEPTFDA70BO17YR03" . "C66487"^^ . "C0023044"^^ . "70BO17YR03"^^ . "The hydrochloride salt form of propiomazine, a phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.NCI" .