"BystolicBRNCI" . "Nebivolol"^^ . "C66221"^^ . "118457-14-0"^^ . . "Pharmacologic Substance"^^ . "CHEBI:64022"^^ . . "FDA"^^ . "NebivololPTNCI" . "NEBIVOLOLPTFDA030Y90569U" . "C22H25F2NO4"^^ . . . "C0068475"^^ . "030Y90569U"^^ . "Nebivolol"^^ . . "Hypertension"^^ . . "A beta-1 adrenergic receptor antagonist with antihypertensive and vasodilatory activity. Nebivolol binds to and blocks the beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, nebivolol potentiates nitric oxide (NO), thereby relaxing vascular smooth muscle and exerting a vasodilatory effect.NCI" . "Nebivolol"^^ .