"2C15H25NO3.C4H4O4"^^ . "Metoprolol Fumarate"^^ . "Metoprolol Fumarate"^^ . . "Metoprolol_Fumarate"^^ . "119637-66-0"^^ . "METOPROLOL FUMARATEPTFDAIO1C09Z674" . "Metoprolol FumaratePTNCI" . "C0350132"^^ . "IO1C09Z674"^^ . "C66133"^^ . . "The fumarate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion.NCI" . . . "FDA"^^ . "Pharmacologic Substance"^^ .