. "Tolterodine"^^ . "A benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.NCI" . "Tolterodine"^^ . . . "C62083"^^ . "FDA"^^ . "C0388753"^^ . "TolterodinePTNCI" . "Organic Chemical"^^ . "Tolterodine_Base"^^ . . "TOLTERODINEPTFDAWHE7A56U7K" . . "CHEBI:9622"^^ . . "124937-51-5"^^ . "C22H31NO"^^ . "Pharmacologic Substance"^^ . "WHE7A56U7K"^^ .