"CHEBI:3011"^^ . . . "Pharmacologic Substance"^^ . "BENAZEPRILPTFDAUDM7Q7QWP8" . "C61645"^^ . "C0053091"^^ . "FDA"^^ . "C24H28N2O5"^^ . . "A carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI" . "Benazepril"^^ . . "Benazepril"^^ . . "UDM7Q7QWP8"^^ . "Benazepril"^^ . "86541-75-5"^^ . "BenazeprilPTNCI" . .