"40793"^^ . "C1522432"^^ . "C585"^^ . . "interleukin-1-betaSYNCI" . "40793"^^ . "Recombinant Interleukin-1-betaPTNCI" . "Amino Acid, Peptide, or Protein"^^ . . "Immunologic Factor"^^ . "Recombinant Interleukin-1-beta"^^ . "Recombinant_Interleukin-1-beta"^^ . "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine interleukin 1 (IL-1)-beta. Produced by monocytes and activated macrophages, endogenous mature IL-1 is generated through proteolytic cleavage by proteases such as IL-1-beta converting enzyme (ICE). This agent promotes angiogenesis, fibroblast proliferation, and neutrophil chemotaxis; it also regulates the functions of lymphocytes and epithelial cells and is involved in the 'acute phase response' to infection. (NCI04)NCI" . "IL-1-bABNCI" . . "Recombinant Interleukin-1-beta"^^ .