_:b766536 _:b680788 . _:b740018 _:b766535 . _:b680787 . "Myeloproliferative Hypereosinophilic Syndrome; Colorectal Cancer; Advanced Prostate Cancer."^^ . _:b766535 _:b766536 . "LitalirSYDTPNSC0032065" . _:b766537 _:b680789 . "SyreaFBNCI" . "Organic Chemical"^^ . "Pharmacologic Substance"^^ . "Chronic Myelogenous Leukemia; Head and Neck Cancer; Malignant Melanoma; Ovarian Carcinoma; Sickle Cell Anemia; Adjuvant in Retroviral Therapy."^^ . _:b766535 _:b680787 . _:b728348 _:b740018 . "X6Q56QN5QC"^^ . "A monohydroxyl-substituted urea (hydroxycarbamate) antimetabolite. Hydroxyurea selectively inhibits ribonucleoside diphosphate reductase, an enzyme required to convert ribonucleoside diphosphates into deoxyribonucleoside diphosphates, thereby preventing cells from leaving the G1/S phase of the cell cycle. This agent also exhibits radiosensitizing activity by maintaining cells in the radiation-sensitive G1 phase and interfering with DNA repair. (NCI04)NCI" . _:b680790 . "Onco-carbideSYDTPNSC0032065" . _:b680792 . . _:b680791 . "127-07-1"^^ . "HydroxyureaPTNCI" . "Hydroxyurea"^^ . _:b680788 . "HydroxyureaSYDTPNSC0032065" . "40685"^^ . _:b680792 . "LitalirFBNCI" . "Onco-CarbideFBNCI" . _:b680787 . . _:b633740 . _:b766540 . _:b680789 . "HydreaSYDTPNSC0032065" . _:b680789 . "40685"^^ . "SQ-1089CNNCI" . _:b740018 . "OxeronFBNCI" . . _:b680790 . "32065"^^ . "HYDROXYUREAPTFDAX6Q56QN5QC" . _:b680792 . _:b680789 . "FDA"^^ . "SQ 1089SYDTPNSC0032065" . "HydreaBRNCI" . _:b680788 . "Hydroxyurea"^^ . _:b680790 . _:b766540 _:b680792 . "HydroxyureaPTDCP00782" . _:b680787 . _:b680788 . _:b680791 . "DroxiaBRNCI" . _:b680791 . . "C0020402"^^ . _:b766539 _:b766540 . "HydroxycarbamideSYNCI" . _:b766538 _:b680790 . "CH4N2O2"^^ . "Hydroxyurea"^^ . _:b633740 _:b728348 . _:b766538 _:b766539 . "CHEBI:44423"^^ . "HydroxyureaSYNCITCGA" . _:b633740 . "hydroxyureaPTNCI-GLOSSCDR0000045308" . _:b766539 _:b680791 . _:b766537 _:b766538 . "HydroxycarbamideSYDTPNSC0032065" . "WR 83799CNNCI" . "C560"^^ . . _:b766536 _:b766537 . _:b728348 . "An anticancer drug that belongs to the family of drugs called antimetabolites.NCI-GLOSS" . "OncocarbideFBNCI" .