"Lidocaine HydrochloridePTNCI" . "XylocitinSYDTPNSC0040030" . "XylocaineBRNCI" . . "V13007Z41A"^^ . "Pharmacologic Substance"^^ . "C14H22N2O.HCl.H2O"^^ . "Lidocaine Hydrochloride"^^ . "XylotoxFBNCI" . "CHEBI:60791"^^ . "FDA"^^ . . "XylocitinBRNCI" . "Lidocaine Hydrochloride"^^ . . "The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.NCI" . . "C0546869"^^ . . . "2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide MonohydrochlorideSNNCI" . "XylocaineSYDTPNSC0040030" . . "XylotoxSYDTPNSC0040030" . "C48000"^^ . "Lidocaine_Hydrochloride"^^ . "6108-05-0"^^ . "LIDOCAINE HYDROCHLORIDEPTFDAV13007Z41A" .