"Estramustine"^^ . . "35LT29625A"^^ . "EstramustinePTNCI" . "CHEBI:4868"^^ . . . "estra-1,3,5(10)triene-317beta-diol 3-[N,N-bis-(2-chloroethyl)carbamate]SNNCI" . . "Estradiol 3-[bis(2-chloroethyl)carbamate]SYDTPNSC0089201" . "17beta-(estra-1,3,5(10)-triene-3,17-diol 3-[bis(2-chloroethyl)carbamate]SNNCI" . "Prostate cancer"^^ . "2998-57-4"^^ . "C0014921"^^ . "Leo 275CNNCI" . "Pharmacologic Substance"^^ . . "FDA"^^ . "C23H31Cl2NO3"^^ . "RO 21-8837CNNCI" . "estramustinePTNCI-GLOSSCDR0000045195" . "estradiol 3-bis(2-chloroethyl)carbamateSNNCI" . "A combination of the hormone estradiol (an estrogen) and nitrogen mustard (an anticancer drug). Used in the palliative therapy of prostate cancer.NCI-GLOSS" . "ESTRAMUSTINEPTFDA35LT29625A" . "Prostate Neoplasm"^^ . "Estramustine"^^ . "A synthetic molecule combining estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic effects. (NCI04)NCI" . . "89201"^^ . "Steroid"^^ . "C479"^^ . "Estramustine"^^ .