"Emtricitabine"^^ . "Pharmacologic Substance"^^ . "FDA"^^ . "EMTRICITABINEPTFDAG70B4ETF4S" . "540668"^^ . "Emtricitabine"^^ . "Emtricitabine"^^ . . "CoviracilBRNCI" . . "EmtrivaBRNCI" . "dOTFCABNCI" . "G70B4ETF4S"^^ . "C8H10FN3O3S"^^ . "(-)-2'-Deoxy-5-fluoro-3'-thiacytidineSNNCI" . "CoviracilSYNCI" . . "FTCSYNCI" . . "EmtricitabinePTNCI" . "540668"^^ . "A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group).NCI" . "BW-524W91CNNCI" . "2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2R-cis)-SNNCI" . "C0909839"^^ . "C47509"^^ . "143491-57-0"^^ . . "CHEBI:31536"^^ . . .