_:b656017 . _:b656017 . _:b656018 . _:b656016 . "CYP2D6_18_Allele"^^ . "C46050"^^ . "Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*18 AlleleSYNCI" . "Human CYP2D6*18 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*18 protein. The CYP2D6*18 allele exhibits a nine nucleotide insertion (g.4125insGTGCCCACT) in exon 9. This alteration increased the Km value of the cytochrome P450 2D6*18 protein toward bufuralol, resulting in decreased enzymatic activity.NCI" . "Cytochrome P450 2D6"^^ . "CYP2D6*18 Allele"^^ . "Gene or Genome"^^ . _:b656017 . "124030"^^ . _:b656018 . "CYP2D6*18SYNCI" . . "C1707214"^^ . "Ethnicity Association: Asian"^^ . _:b656015 . "CYP2D6*18 AllelePTNCI" . _:b656016 . _:b656014 . _:b656014 . _:b656015 . "NM_000106"^^ . _:b656014 . _:b656015 . _:b656014 . "CYP2D6(J9)SYNCI" . "CYP2D6*18 Allele"^^ . _:b656018 . "8946471"^^ . _:b656015 . _:b656016 . _:b656017 . . _:b656018 . "CYP2D6, g.4125insGTGCCCACTSYNCI" . _:b656016 .