_:b656222 . _:b656224 . _:b656222 . _:b656223 . "Ethnicity Association: African American"^^ . _:b656216 . _:b656224 . _:b656219 . . _:b656220 . "NM_000777"^^ . _:b656221 . "C1707236"^^ . "CYP3A5*6 Allele"^^ . _:b656222 . _:b656224 . _:b656218 . _:b656221 . _:b656217 . _:b656223 . _:b656219 . "CYP3A5_6_Allele"^^ . _:b656223 . "Human CYP3A5*6 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form of the human CYP3A5 wild-type allele, encodes cytochrome P450 3A5*6 protein. The CYP3A5*6 allele exhibits a clinically-relevant SNP (g.14690G>A), resulting in deletion of exon 7 from the splice variant, a frame shift and premature stop at 184 amino acids. Truncation of the cytochrome P450 3A5*6 protein causes complete loss of enzymatic activity.NCI" . _:b656216 . _:b656216 . _:b656217 . "CYP3A5, g.14690G>ASYNCI" . _:b656220 . _:b656222 . "CYP3A5*6SYNCI" . "C46022"^^ . "605325"^^ . _:b656223 . _:b656218 . "Gene or Genome"^^ . _:b656219 . _:b656220 . "Cytochrome P450, Family 3, Subfamily A, Polypeptide 5*6 AlleleSYNCI" . . _:b656224 . _:b656221 . "CYP3A5*6 AllelePTNCI" . "11279519"^^ . "CYP3A5*6 Allele"^^ . _:b656216 . _:b656217 . _:b656218 . _:b656218 . _:b656217 . _:b656219 . _:b656220 . _:b656221 .