"CYP2C19*1 Allele"^^ . "7487078"^^ . . _:b655774 . "CYP2C19*1 AllelePTNCI" . "12464799"^^ . _:b655772 . "NM_000769"^^ . _:b655772 . _:b655773 . _:b655773 . _:b655773 . _:b655774 . _:b655771 . "124020"^^ . "2009263"^^ . "Human CYP2C19*1 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*1 protein. There are multiple haplotypes of this allele. The nucleotide sequence of CYP2C19*1A is identical to that of the wild-type allele and exhibits no mutations. CYP2C19*1B and CYP2C19*1C both exhibit a SNP (c.991A>G) in exon 7 that results in an I331V coding change. This alteration in protein sequence has no effect on the enzymatic activity of the corresponding cytochrome P450 2C19*1 proteins.NCI" . _:b655771 . "CYP2C19, wild-typeSYNCI" . _:b655771 . _:b655774 . "CYP2C19*1SYNCI" . "Cytochrome P450 2C19"^^ . _:b655771 . "C45598"^^ . "C1707180"^^ . _:b655772 . "rs3758581"^^ . "Gene or Genome"^^ . "CYP2C19, c.991A>GSYNCI" . "Cytochrome P450, Family 2, Subfamily C, Polypeptide 19*1 AlleleSYNCI" . . "CYP2C19*1 Allele"^^ . "CYP2C19_1_Allele"^^ . _:b655772 . _:b655774 . "CYP2C19, I331VSYNCI" . _:b655773 .