. "High Affinity Interleukin 12 Receptor BetaSYNCI" . "Interleukin-12_Receptor"^^ . "Interleukin 12 Receptor"^^ . "Interleukin 12 ReceptorSYNCI" . "Interleukin 12 Receptor BetaSYNCI" . "Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2 Chain (IL12RB2), each a type I transmembrane disulfide-linked dimer/oligomer protein containing 5 FNIII domains, a box 1 motif required for JAK interaction/activation, and a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. Involved in IL12 signal transduction, IL12RB1 and IL12RB2 oligomers act as low affinity IL12 receptors. (NCI)NCI" . . . "C0255732"^^ . "C38915"^^ . . "Receptor"^^ . "Amino Acid, Peptide, or Protein"^^ . "High Affinity Interleukin 12 ReceptorSYNCI" . "Interleukin 12 ReceptorPTNCI" . "Human high affinity Interleukin 12 Receptor Beta (Type I Cytokine Receptor 2 Family) is composed of Interleukin 12 Receptor Beta 1 Chain (IL12RB1 Gene) and Interleukin 12 Receptor Beta 2 Chain (IL12RB2 Gene), both type I transmembrane proteins involved in signal transduction and each containing 5 FNIII domains; a box 1 motif required for JAK interaction/activation; and a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. IL12RB1/2 activity appears to contribute to host defense mechanisms and the inflammatory response. Both IL12RB1 oligomers and IL12RB2 oligomers act as a low affinity IL12 receptor. (NCI)NCI" . "Interleukin 12 Receptor"^^ .