. . "335308"^^ . . "C374"^^ . "C0008783"^^ . "cimetidinePTNCI-GLOSSCDR0000045184" . . "A histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T lymphocyte activity and to inhibit natural killer (NK) cell activity and interleukin-2 production. Cimetidine also may inhibit tumor growth by suppressing histamine's growth-factor activity and blocking histamine-induced stimulation of vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor. (NCI04)NCI" . "Gastrointestinal conditions; allergic reaction prevention; immune modulation"^^ . "Pharmacologic Substance"^^ . "TagametSYDTPNSC0335308" . "Amino Acid, Peptide, or Protein"^^ . "80061L1WGD"^^ . "CimetidinePTDCP01655" . "Guanidine, N''-Cyano-N-Methyl-N'-(2-(((5-Methyl-1H-Imidazol-4-yl)Methyl)Thio)Ethyl)-SNNCI" . "FDA"^^ . . "39185"^^ . "A drug usually used to treat stomach ulcers and heartburn. It is also commonly used in a regimen to prevent allergic reactions.NCI-GLOSS" . "Cimetidine"^^ . "39185"^^ . . "TagametBRNCI" . "Cimetidine"^^ . "CIMETIDINEPTFDA80061L1WGD" . "Cimetidine"^^ . "N-Cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidineSNNCI" . "C10H16N6S"^^ . . "CimetidinePTNCI" . "51481-61-9"^^ . "CHEBI:3699"^^ .