. "A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.NCI" . "39177"^^ . "Organic Chemical"^^ . . . . "CHEBI:204928"^^ . . "Cefotaxime"^^ . "Antibiotic"^^ . "FDA"^^ . "CEFOTAXIMEPTFDAN2GI8B1GK7" . "39177"^^ . "CefotaximePTNCI" . "C0007554"^^ . "C354"^^ . "Cefotaxime"^^ . "Cefotaxime"^^ . . "63527-52-6"^^ . "N2GI8B1GK7"^^ . "C16H17N5O7S2"^^ .