"Pharmacologic Substance"^^ . "37821"^^ . "C18H20N4"^^ . "LerisetronPTNCI" . "F-0930-RS2CNNCI" . "C30143"^^ . . . "FDA"^^ . "Q36R82SXRG"^^ . "1-Phenyl-Methyl-2-Piperazinyl-1H-Benzimidazole HydrochlorideSNNCI" . "Lerisetron"^^ . . "LERISETRONPTFDAQ36R82SXRG" . "143257-98-1"^^ . "A substance being studied in the treatment of nausea and vomiting caused by cancer treatment. Lerisetron is a type of serotonin receptor antagonist and a type of antiemetic.NCI-GLOSS" . "C0758799"^^ . "Lerisetron"^^ . "37821"^^ . "Lerisetron"^^ . "Organic Chemical"^^ . "lerisetronPTNCI-GLOSSCDR0000044876" . "The hydrochloride salt of a 2-piperazinylbenzimidazole-derivative serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Lerisetron specifically binds to 5-HT3 receptors, located peripherally on vagus nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, which may result in suppression of chemotherapy-induced nausea and vomiting.NCI" . . .