"DetrolBRNCI" . . "DetrusitolBRNCI" . . "124937-52-6"^^ . . "The tartrate salt form of tolterodine, a benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine receptor binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract.. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.NCI" . "Pharmacologic Substance"^^ . "C29504"^^ . . "C0719805"^^ . "5T619TQR3R"^^ . . . "Tolterodine Tartrate"^^ . "TOLTERODINE TARTRATEPTFDA5T619TQR3R" . "Tolterodine TartratePTNCI" . "FDA"^^ . "Tolterodine"^^ . "CHEBI:32245"^^ . "Tolterodine Tartrate"^^ . "C22H31NO.C4H6O6"^^ .