"DuocarmycinsSYNCI" . "C2156"^^ . "A spirocyclopropylhexadienone-containing antineoplastic antibiotic isolated from Streptomyces bacterial species or derived synthetically. Duocarmycin antibiotics alkylate DNA by binding to adenine-thymine (A-T)- rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and inducing apoptosis.NCI" . "Duocarmycin Antineoplastic Antibiotic"^^ . "Duocarmycin_Antibiotic"^^ . "C1512091"^^ . "Duocarmycin Antineoplastic AntibioticPTNCI" . . "Duocarmycin Antineoplastic Antibiotic"^^ . . . "Chemical Viewed Functionally"^^ .