"Bayer 205CNNCI" . _:b716390 . . _:b716392 . "African trypanosomiasis; onchocerciasis"^^ . "Suramin_Sodium"^^ . "309 FSYDTPNSC0034936" . "MoranylFBNCI" . "A sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.NCI" . "8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-1,3,5-naphthalenetrisulfonic Acid Hexasodium SaltSNNCI" . "Bayer 205SYDTPNSC0034936" . "Suramin SodiumPTNCI" . "GermaninSYDTPNSC0034936" . "AntrypolFBNCI" . . "NaphurideFBNCI" . "Suramin Sodium"^^ . "34936"^^ . "NaganinumFBNCI" . _:b716390 . _:b716389 . "SURAMIN SODIUMPTFDA89521262IH" . _:b716391 . "Sodium SuraminSYNCI" . . . _:b716392 . _:b716393 . . "MetaretBRNCI" . _:b716394 . _:b716389 . "Bladder cancer; breast cancer; non-small cell lung cancer"^^ . _:b716391 . _:b716389 . . _:b716389 . _:b716390 . _:b716391 . "C51H34N6O23S6.6Na"^^ . . "GermaninFBNCI" . "C1848"^^ . _:b716393 . _:b716394 . "89521262IH"^^ . "Suramin HexasodiumPTDCP30140" . "AntrypolSYDTPNSC0034936" . "309 FFBNCI" . "Suramin Sodium"^^ . "NaganolFBNCI" . "Fourneau 309SYDTPNSC0034936" . "NaganinSYDTPNSC0034936" . _:b716392 . "Organic Chemical"^^ . "BelganylFBNCI" . . "129-46-4"^^ . . "NaganinFBNCI" . "CI-1003CNNCI" . "Fourneau 309FBNCI" . _:b716394 . _:b716393 . "FDA"^^ . "NaganolSYDTPNSC0034936" . "Sodium suraminSYDTPNSC0034936" . "C0813205"^^ . "Suramin sodiumSYDTPNSC0034936" . _:b716392 . "Suramin HexasodiumSYNCI" . _:b716393 . "Pharmacologic Substance"^^ . _:b716390 . _:b716394 . "MoranylSYDTPNSC0034936" . _:b716391 .