. "AG3340CNNCI" . "Prinomastat"^^ . "PrinomastatPTNCI" . "C0919273"^^ . "FDA"^^ . "43058"^^ . "An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Prinomastat is a matrix metalloproteinase inhibitor.NCI-GLOSS" . "AG3340PTNCI-GLOSSCDR0000044862" . . "Prinomastat"^^ . "Pharmacologic Substance"^^ . . . "prinomastatPTNCI-GLOSSCDR0000046016" . "PRINOMASTATPTFDA10T6626FRK" . "C18H21N3O5S2"^^ . "Organic Chemical"^^ . "10T6626FRK"^^ . "192329-42-3"^^ . "A synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier. (NCI04)NCI" . "(3S)-N-Hydroxy-2,2-dimethyl-4-{{4-(4-piridinyloxy)phenyl}sulfonyl}-3-thiomorpholinecarboxamideSNNCI" . "Prinomastat"^^ . "PrinomastatPTDCP31682" . "C1811"^^ . "43058"^^ .