"Enzyme"^^ . _:b664522 . . _:b756897 _:b664521 . _:b664523 . _:b664523 . _:b756896 _:b664520 . "Amino Acid, Peptide, or Protein"^^ . _:b664520 . "P450-2D6SYNCI" . "Cytochrome P450, Subfamily IIDSYNCI" . _:b756899 _:b664523 . _:b664521 . _:b756898 _:b664522 . _:b756900 _:b756901 . "Cytochrome P450 2D6"^^ . "Cytochrome P450 Subfamily IID Polypeptide 6SYNCI" . "Cytochrome P450-DB1SYNCI" . "Cytochrome-P450-2D6"^^ . _:b664526 . "Cytochrome P450 2D6PTNCI" . _:b756900 _:b664524 . _:b664526 . . _:b756901 _:b756902 . _:b664526 . _:b756901 _:b664525 . _:b664524 . _:b756902 _:b664526 . "C0057223"^^ . _:b739112 . _:b664523 . "Debrisoquine 4-HydroxylaseSYNCI" . _:b664525 . _:b756897 _:b756898 . "EC 1.14.14.1SYNCI" . _:b756896 _:b756897 . _:b664520 . _:b631776 _:b739112 . _:b664521 . "Microsomal MonooxygenaseSYNCI" . "P10635"^^ . _:b756899 _:b756900 . "Flavoprotein-Linked MonooxygenaseSYNCI" . "CYPIID6SYNCI" . "Cytochrome P450 2D6 (497 aa, ~56 kDa) is encoded by the human CYP2D6 gene. This protein plays a role in flavoprotein metabolism.NCI" . _:b664522 . _:b664520 . "124030"^^ . _:b756898 _:b756899 . _:b756902 . _:b664524 . _:b631776 . _:b756895 _:b756896 . _:b664519 . "Cytochrome P450, Subfamily IID-Like 1SYNCI" . _:b664525 . "CYP2D6SYNCI" . "Xenobiotic MonooxygenaseSYNCI" . "P450DB1SYNCI" . _:b664522 . _:b756895 _:b664519 . "Cytochrome P450 2D6"^^ . _:b664519 . _:b664519 . . "Cytochrome P450 2D6 localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrhythmic drugs; and amitriptyline, an anti-depressant."^^ . _:b631776 . _:b664525 . _:b664521 . "C17287"^^ . _:b664524 . _:b739112 _:b756895 . "P450-DB1SYNCI" .