_:b767813 _:b767814 . _:b682850 . _:b682841 . _:b682841 . _:b633992 . "EC 2.7.10.1SYNCI" . _:b682851 . _:b767814 _:b767815 . _:b682840 . "CD220SYNCI" . _:b767825 . _:b682848 . _:b682849 . _:b767809 _:b767810 . "C0034818"^^ . _:b682839 . _:b682849 . "P06213"^^ . "147670"^^ . _:b682854 . _:b633992 . _:b682855 . _:b767811 _:b767812 . _:b682842 . _:b682852 . _:b682847 . _:b767810 _:b767811 . _:b682852 . _:b682843 . "Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis.NCI" . _:b682853 . _:b682853 . _:b767822 _:b767823 . _:b682846 . _:b682840 . _:b767820 _:b767821 . _:b682841 . "Insulin receptor is cleaved to generate and alpha chain and a beta chain. The mature receptor is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. (UniProt)"^^ . _:b682846 . _:b767821 _:b767822 . _:b682843 . "Amino Acid, Peptide, or Protein"^^ . _:b682847 . _:b767824 _:b682854 . . _:b767819 _:b767820 . _:b682848 . _:b682851 . "Insulin ReceptorPTNCI" . _:b682844 . _:b767818 _:b767819 . _:b767823 _:b767824 . _:b767825 _:b682855 . _:b682849 . _:b682845 . _:b767817 _:b767818 . . _:b682844 . _:b767816 _:b767817 . _:b682850 . _:b682845 . _:b682851 . _:b730610 . _:b682846 . "IRSYNCI" . "Antigen CD220SYNCI" . _:b682852 . _:b682847 . _:b682855 . "CD220 AntigenSYNCI" . "Insulin Receptor"^^ . _:b767813 _:b682843 . _:b682854 . _:b767819 _:b682849 . _:b767824 _:b767825 . _:b767812 _:b682842 . _:b682853 . _:b767818 _:b682848 . _:b682850 . _:b682839 . _:b682842 . _:b767814 _:b682844 . . _:b682843 . _:b767815 _:b682845 . _:b682845 . _:b682844 . _:b767822 _:b682852 . _:b767823 _:b682853 . _:b767821 _:b682851 . "Insulin_Receptor"^^ . "C17072"^^ . _:b767811 _:b682841 . _:b767820 _:b682850 . _:b767809 _:b682839 . _:b767810 _:b682840 . _:b682855 . _:b682848 . "Insulin Receptor"^^ . _:b633992 _:b730610 . _:b682842 . "INSRSYNCI" . "Enzyme"^^ . _:b767816 _:b682846 . _:b767817 _:b682847 . _:b682854 . _:b682840 . _:b767815 _:b767816 . _:b767812 _:b767813 . _:b682839 . _:b730610 _:b767809 .