. "Amino Acid, Peptide, or Protein"^^ . "C1692"^^ . "GastrimmuneBRNCI" . "C0935889"^^ . "G17DTABNCI" . "Gastrin ImmunotoxinPTNCI" . "Pharmacologic Substance"^^ . "38352"^^ . . . "38352"^^ . "Neutralizing G17 HormoneSYNCI" . "Gastrin_Immunotoxin"^^ . "Neutralize Hormone G17SYNCI" . "An immunotoxin containing an epitope of human gastrin conjugated to diphtheria toxin, with antineoplastic activity. The gastrin epitope in this vaccine is chemically identical or similar to the endogenous gastrin-17 (G-17), a 17-amino acid peptide hormone that stimulates secretion of gastric acid by the stomach. Diphtheria toxin inhibits protein synthesis via modifying translation elongation factor 2 (EF-2). Vaccination with this immunotoxin may elicit production of antibodies against gastrinoma cells overexpressing gastrin, in addition to the toxic effects on protein synthesis exerted by the diphtheria toxin moiety.NCI" . "G17DT ImmunogenSYNCI" . "Gastrin Immunotoxin"^^ . "Stomach, Colon, Rectal, Liver, Esophageal, and Pancreatic Cancer."^^ . "Gastrin Immunotoxin"^^ . "Anti-gastrin 17SYNCI" . "Anti-Gastrin Therapeutic VaccineSYNCI" .