. "Pharmacologic Substance"^^ . "Localized metastatic bone pain"^^ . "ibandronatePTNCI-GLOSSCDR0000377709" . "365963"^^ . "IBANDRONATE SODIUMPTFDAJ12U072QL0" . "BonivaBRNCI" . "FDA"^^ . "A drug that is used to prevent and treat osteoporosis, and is being studied in the treatment of cancer that has spread to the bones. It belongs to the family of drugs called bisphosphonates.NCI-GLOSS" . "365963"^^ . "BondronateFBNCI" . "Ibandronate Sodium"^^ . "Ibandronate Sodium"^^ . "J12U072QL0"^^ . "C0772244"^^ . "The sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain.NCI" . . "Osteoporosis, treatment and prevention"^^ . "C9H22NO7P2.Na.H2O"^^ . "138926-19-9"^^ . . "C1670"^^ . . "Ibandronate SodiumPTNCI" . "Ibandronate"^^ . "Organophosphorus Compound"^^ . . "Ibandronate SodiumPTDCP20612" .