"ProthromadinSYNCI" . . "Warfarin Sodium"^^ . "Warfarin_Sodium"^^ . "WaranFBNCI" . "CHEBI:10034"^^ . "C1658"^^ . "CoumadinBRNCI" . "MarevanFBNCI" . "Warfarin Sodium"^^ . . "The sodium salt form of warfarin, a coumarin and a vitamin K antagonist, with anticoagulant activity. Warfarin sodium inhibits both vitamin K and vitamin K epoxide reductases, thereby interfering with the cyclic interconversion of vitamin K epoxide to its reduced form, vitamin KH2. Vitamin KH2 is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins. As a result, maturation of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Without these coagulation factors, thrombogenesis and blood clot formation are prevented.NCI" . . "ProthromadinSYDTPNSC0059813" . . "Pharmacologic Substance"^^ . "Organic Chemical"^^ . "C0699129"^^ . "C19H15O4.Na"^^ . "WarfiloneFBNCI" . "TintoraneSYNCI" . . "PanwarfinBRNCI" . . "129-06-6"^^ . "CoumadinSYDTPNSC0059813" . "6153CWM0CL"^^ . . "PanwarfinSYDTPNSC0059813" . "Warfarin SodiumPTNCI" . "WARFARIN SODIUMPTFDA6153CWM0CL" . "FDA"^^ .