"FDA"^^ . "L-OddcCNNCI" . "C1438"^^ . "2(1H)-Pyrimidinone, 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-SNNCI" . "BCH-4556CNNCI" . "C8H11N3O4"^^ . "TroxacitabinePTNCI" . "Pharmacologic Substance"^^ . "A dioxolane derivative and a novel L-configuration deoxycytidine analogue with potent antineoplastic activity. When incorporated into growing chain during DNA replication, troxacitabine stops DNA polymerization due to its unnatural L-configuration, in contrast to the normal nucleotides with D-configuration. As a result, this agent terminates DNA synthesis upon incorporated into DNA molecules, and consequently interrupts tumor cell proliferation.NCI" . "Chronic myelogenous leukemia"^^ . . . "TROXACITABINEPTFDA60KQZ0388Y" . . "Troxacitabine"^^ . "C0877874"^^ . "A drug being studied for use as an anticancer agent.NCI-GLOSS" . "Nucleic Acid, Nucleoside, or Nucleotide"^^ . "43646"^^ . "145918-75-8"^^ . "troxacitabinePTNCI-GLOSSCDR0000046760" . "TroxatylBRNCI" . "Troxacitabine"^^ . "Troxacitabine"^^ . "60KQZ0388Y"^^ . "43646"^^ . .