"RIFABUTINPTFDA1W306TDA6S" . "C0140575"^^ . "A drug used to prevent the spread of a bacterium called in patients with advanced HIV (the virus that causes AIDS) infection. It blocks an enzyme that the bacteria need to grow. It is a type of antibiotic.NCI-GLOSS" . . "RifabutinPTNCI" . "37812"^^ . "Rifabutin"^^ . "CHEBI:45367"^^ . "MycobutinPTNCI-GLOSSCDR0000663313" . . "MycobutinBRNCI" . . "72559-06-9"^^ . . . "Rifabutin"^^ . "Antibiotic"^^ . "FDA"^^ . "Organic Chemical"^^ . "Prevention and treatment of Mycobacterium avium complex (MAC) and tuberculosis in patients with HIV infection"^^ . "A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.MSH2002_06_01" . "37812"^^ . "1W306TDA6S"^^ . "A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. (NCI04)NCI" . "C46H62N4O11"^^ . "Rifabutin"^^ . . "rifabutinPTNCI-GLOSSCDR0000663309" . "C1408"^^ .