_:vb697824 . _:vb697824 . "O(6)-benzylguaninePTNCI-GLOSSCDR0000046040" . "O_6_Benzylguanine"^^ . "O6-BenzylguanineSYDTPNSC0637037" . _:vb636286 . . _:vb777388 _:vb697826 . "O6-BenzylguaninePTNCI" . . "A guanine analogue with antineoplastic activity. O6-benzylguanine binds the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase (AGT), transferring the benzyl moiety to the active-site cysteine and resulting in inhibition of AGT-mediated DNA repair. Co-administration of this agent potentiates the effects of other chemotherapeutic agents that damage DNA. (NCI04)NCI" . _:vb697825 . "A drug that may improve the response of cancer cells to chemotherapy.NCI-GLOSS" . "O6-BenzylguanineSNNCI" . _:vb697826 . "2-amino-6-(benzyloxy)purineSNNCI" . "2-amino-6-(phenylmethoxy)-9h-purineSNNCI" . . "42113"^^ . "Nucleic Acid, Nucleoside, or Nucleotide"^^ . "O6-Benzylguanine"^^ . _:vb697826 . "C0083812"^^ . "42113"^^ . _:vb636286 . "6-O-BenzylguanineSYDTPNSC0637037" . _:vb697824 . _:vb736735 _:vb777386 . _:vb697825 . _:vb697825 . "FDA"^^ . "6-O-BENZYLGUANINEPTFDA01KC87F8FE" . _:vb736735 . "O(6)-BenzylguanineSYNCI" . _:vb777387 _:vb697825 . _:vb777387 _:vb777388 . _:vb777386 _:vb777387 . _:vb777386 _:vb697824 . "Pharmacologic Substance"^^ . "C12H11N5O"^^ . _:vb697826 . "O-6-BenzylguanineSNNCI" . . "01KC87F8FE"^^ . "O6-Benzylguanine"^^ . "C1306"^^ . "637037"^^ . _:vb777388 . _:vb636286 _:vb736735 . "19916-73-5"^^ .