"OriconazoleSYNCI" . . _:b684460 . "SporanoxBRNCI" . . "FDA"^^ . "(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-oneSNNCI" . "Antibiotic"^^ . "Fungal Infections"^^ . . "C1138"^^ . "itraconazolePTNCI-GLOSSCDR0000045161" . "Itraconazole"^^ . "39106"^^ . "A drug used to prevent or treat fungal infections. It belongs to the family of drugs called antifungal agents.NCI-GLOSS" . _:b684460 . "ITRACONAZOLEPTFDA304NUG5GF4" . _:b684460 . . "A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fugal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections. (NCI04)NCI" . "ItraconazolePTNCI" . "39106"^^ . "Acute myeloid leukemia; chemotherapy-induced fungal infection; myelodysplasic syndrome"^^ . "Itraconazole"^^ . "C0064113"^^ . "Itraconazole"^^ . "Organic Chemical"^^ . "84625-61-6"^^ . "CHEBI:6076"^^ . "R 51,211CNNCI" . _:b684460 . "304NUG5GF4"^^ . . "C35H38Cl2N8O4"^^ . .