"Cefepime"^^ . "MaxipimeBRNCI" . "C1041"^^ . . "38350"^^ . "123171-59-5"^^ . "C19H24N6O5S2.2ClH.H2O"^^ . "CHEBI:31368"^^ . . . . "38350"^^ . "The hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefepime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins.NCI" . "Pyrrolidinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methyl-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-SNNCI" . . "CEFEPIME HYDROCHLORIDEPTFDAI8X1O0607P" . "Organic Chemical"^^ . "C0771284"^^ . "Cefepime Hydrochloride"^^ . "I8X1O0607P"^^ . "Antibiotic"^^ . "Upper respiratory tract and urinary tract infections; febrile neutropenic conditions"^^ . . "Cefepime Hydrochloride"^^ . "Cefepime HydrochloridePTNCI" . "FDA"^^ .