"27022"^^ . "27369"^^ . . "Ve farmakokinetick\u00E9 studii bylo pozorov\u00E1no p\u0159i sou\u010Dasn\u00E9m pod\u00E1v\u00E1n\u00ED diltiazemu 2,7 n\u00E1sobn\u00E9 zv\u00FD\u0161en\u00ED expozice kyselin\u011B simvastatinov\u00E9, zp\u016Fsoben\u00E9 pravd\u011Bpodobn\u011B inhibic\u00ED CYP3A4. Proto by d\u00E1vka simvastatinu nem\u011Bla u pacient\u016F u\u017E\u00EDvaj\u00EDc\u00EDch sou\u010Dasn\u011B diltiazem p\u0159ekro\u010Dit\u00A040\u00A0mg /den, pokud by klinick\u00FD p\u0159\u00EDnos nep\u0159ev\u00E1\u017Eil zv\u00FD\u0161en\u00E9 riziko myopatie a rhabdomyol\u00FDzy."@cs . . "2"^^ . .