. . . . . . . . . "Tabulka \u010D. 2: Ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky hl\u00E1\u0161en\u00E9 p\u0159i u\u017Eit\u00ED samotn\u00E9ho irbesartanu\nCelkov\u00E9 poruchy a reakce v M\u00E9n\u011B \u010Dast\u00E9: bolest na hrudi\nm\u00EDst\u011B aplikace: \n \nTabulka \u010D. 3 : Ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky pozorovan\u00E9 p\u0159i pod\u00E1v\u00E1n\u00ED samotn\u00E9ho hydrochlorothiazidu \n(bez ohledu na vztah k l\u00E9\u010Div\u00E9mu p\u0159\u00EDpravku)\nVy\u0161et\u0159en\u00ED: \t Nen\u00ED zn\u00E1mo: \t elektrolytov\u00E1 dysbalance (v\u010Detn\u011B\n hypokal\u00E9mie a hyponatr\u00E9mie, viz\n bod 4.4), hyperurik\u00E9mie, glykosurie,\n hyperglyk\u00E9mie, vzestup hladiny\n cholesterolu a triglycerid\u016F\nSrde\u010Dn\u00ED poruchy: \tNen\u00ED zn\u00E1mo: \tsrde\u010Dn\u00ED arytmie\nPoruchy krve a lymfatick\u00E9ho\t Nen\u00ED zn\u00E1mo: \t aplastick\u00E1 an\u00E9mie, \u00FAtlum kostn\u00ED d\u0159en\u011B,\nsyst\u00E9mu: neutrop\u00E9nie/agranulocyt\u00F3za,\n hemolytick\u00E1 an\u00E9mie, leukop\u00E9nie,\n trombocytop\u00E9nie\t\t\nPoruchy nervov\u00E9ho syst\u00E9mu: \tNen\u00ED zn\u00E1mo: \tz\u00E1vrat\u011B, parest\u00E9zie, pocit na omdlen\u00ED,\n neklid\nPoruchy oka:\tNen\u00ED zn\u00E1mo: \tp\u0159echodn\u00E9 poruchy vid\u011Bn\u00ED, \u017Elut\u00E9 vid\u011Bn\u00ED \nRespira\u010Dn\u00ED, hrudn\u00ED a \tNen\u00ED zn\u00E1mo: \tdechov\u00E1 t\u00EDse\u0148 (v\u010Detn\u011B pneumonitidy a\nmediastin\u00E1ln\u00ED poruchy:\t\t plicn\u00EDho ed\u00E9mu)\nGastrointestin\u00E1ln\u00ED poruchy: \tNen\u00ED zn\u00E1mo: \tpankreatitida, anorexie, pr\u016Fjem, \n\t\t z\u00E1cpa, podr\u00E1\u017Ed\u011Bn\u00ED \u017Ealude\u010Dn\u00ED sliznice,\n sialoadenitida, ztr\u00E1ta chuti\n \nPoruchy ledvin a mo\u010Dov\u00FDch cest: \tNen\u00ED zn\u00E1mo: interstici\u00E1ln\u00ED nefritida, ren\u00E1ln\u00ED dysfunkce\nPoruchy k\u016F\u017Ee a podko\u017En\u00ED Nen\u00ED zn\u00E1mo: \tanafylaktick\u00E9 reakce, toxick\u00E1 epiderm\u00E1ln\u00ED \ntk\u00E1n\u011B: \t\tnekrol\u00FDza, nekrotizuj\u00EDc\u00ED angiitida (vaskulitida,\n\t\tko\u017En\u00ED vaskulitida), reakce podobn\u00E9 ko\u017En\u00EDmu \n\t\tlupus erythematodes, reaktivace \n\t\tko\u017En\u00EDho lupus erythematodes, \n\t\t fotosenzitivn\u00ED reakce, vyr\u00E1\u017Eka, kop\u0159ivka\nPoruchy svalov\u00E9 a kostern\u00ED \t Nen\u00ED zn\u00E1mo: \tslabost, svalov\u00FD spasmus \nSoustavy a pojivov\u00E9 tk\u00E1n\u011B: \t\t\nC\u00E9vn\u00ED poruchy: \tNen\u00ED zn\u00E1mo: \tpostur\u00E1ln\u00ED hypotenze \nCelkov\u00E9 poruchy a reakce \tNen\u00ED zn\u00E1mo: \thore\u010Dka\nv m\u00EDst\u011B aplikace:\nPoruchy jater a \u017Elu\u010Dov\u00FDch cest: \tNen\u00ED zn\u00E1mo: \t\u017Eloutenka (intrahepat\u00E1ln\u00ED cholestatick\u00E1\n \u017Eloutenka)\nPsychiatrick\u00E9 poruchy: \tNen\u00ED zn\u00E1mo: \tdeprese, poruchy sp\u00E1nku \nNa d\u00E1vce z\u00E1visl\u00E9 ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky hydrochlorothiazidu (zejm\u00E9na poruchy elektrolyt\u016F) se mohou p\u0159i titraci hydrochlorothiazidu zvy\u0161ovat."@cs . . . . . . . . . . . . . "27001"^^ . "1"^^ . . . . . . . . . "23988"^^ . . . . . . . . . . . . . . . .