. . "9644"^^ . . . . . "1"^^ . "Sou\u010Dasn\u00E9 pod\u00E1v\u00E1n\u00ED inhibitoru prote\u00E1zy HIV - ritonaviru, co\u017E je vysoce \u00FA\u010Dinn\u00FD inhibitor P450, p\u0159i jeho ust\u00E1len\u00E9 hladin\u011B (500\u00A0mg dvakr\u00E1t denn\u011B) spolu se sildenafilem (100 mg v\u00A0jedn\u00E9 d\u00E1vce) vedlo ke 300% (4n\u00E1sobn\u00E9mu) zv\u00FD\u0161en\u00ED Cmax sildenafilu a\u00A01000% (11n\u00E1sobn\u00E9mu) zv\u00FD\u0161en\u00ED plazmatick\u00E9 AUC sildenafilu."@cs . "9347"^^ . .