"33543"^^ . "Biotransformace escitalopramu na demetylovan\u00FD metabolit se prim\u00E1rn\u011B zprost\u0159edkov\u00E1v\u00E1 syst\u00E9mem CYP2C19. Je mo\u017En\u00E1 ur\u010Dit\u00E1 \u00FA\u010Dast enzym\u016F CYP3A4 a CYP2D6.\nEliminace\nPolo\u010Das eliminace (t\u00BD \u03B2) po opakovan\u00E9m pod\u00E1v\u00E1n\u00ED je zhruba 30 hodin a peror\u00E1ln\u00ED plazmatick\u00E1 clearance (Cloral) je zhruba 0,6 litr\u016F/min."@cs . . "33251"^^ . . . . "5"^^ .