. . . . . . . . . . . . . . . . . . . . "25076"^^ . . . . . "1"^^ . . . . . . . "27024"^^ . . . . . . . . . . . . . . . . . . . "Tabulka \u010D.2: Ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky hl\u00E1\u0161en\u00E9 p\u0159i u\u017Eit\u00ED samotn\u00E9ho irbesartanu\nCelkov\u00E9 poruchy a reakce v m\u00EDst\u011B aplikace:\nM\u00E9n\u011B \u010Dast\u00E9: \tbolest na hrudi\nTabulka \u010D.3: Ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky pozorovan\u00E9 p\u0159i pod\u00E1v\u00E1n\u00ED samotn\u00E9ho hydrochlorothiazidu\n(bez ohledu na vztah k l\u00E9\u010Div\u00E9mu p\u0159\u00EDpravku)\nV\u00EDcen\u00E1sobn\u00E1 vy\u0161et\u0159en\u00ED \nNen\u00ED zn\u00E1mo: \telektrolytov\u00E1 dysbalance (zahrnuj\u00EDc\u00ED hypokal\u00E9mii a hyponatr\u00E9mii, viz bod 4.4), hyperurik\u00E9mie, glykosurie, hyperglyk\u00E9mie, vzestup hladiny cholesterolu a triacylglycerol\u016F\nSrde\u010Dn\u00ED poruchy:\nNen\u00ED zn\u00E1mo: \tsrde\u010Dn\u00ED arytmie\nPoruchy krve a lymfatick\u00E9ho syst\u00E9mu\nNen\u00ED zn\u00E1mo: \taplastick\u00E1 an\u00E9mie, \u00FAtlum kostn\u00ED d\u0159en\u011B, neutropenie/agranulocyt\u00F3za, hemolytick\u00E1 an\u00E9mie, leukopenie, trombocytopenie\nPoruchy nervov\u00E9ho syst\u00E9mu:\nNen\u00ED zn\u00E1mo: \tz\u00E1vrat\u011B, parest\u00E9zie, pocit na omdlen\u00ED, neklid\nPoruchy oka:\nNen\u00ED zn\u00E1mo: \tp\u0159echodn\u00E9 poruchy vid\u011Bn\u00ED, \u017Elut\u00E9 vid\u011Bn\u00ED\nRespira\u010Dn\u00ED, hrudn\u00ED a mediastin\u00E1ln\u00ED poruchy:\nNen\u00ED zn\u00E1mo: \tdechov\u00E1 t\u00EDse\u0148 (zahrnuj\u00EDc\u00ED pneumonitidu a plicn\u00ED ed\u00E9m)\nGastrointestin\u00E1ln\u00ED poruchy:\nNen\u00ED zn\u00E1mo: \tpankreatitida, anorexie, pr\u016Fjem, z\u00E1cpa, podr\u00E1\u017Ed\u011Bn\u00ED \u017Ealude\u010Dn\u00ED sliznice, sialoadenitida, ztr\u00E1ta chuti\nPoruchy ledvin a mo\u010Dov\u00FDch cest\nNen\u00ED zn\u00E1mo: \tinterstici\u00E1ln\u00ED nefritida, ren\u00E1ln\u00ED dysfunkce\nPoruchy k\u016F\u017Ee a podko\u017En\u00ED tk\u00E1n\u011B\nNen\u00ED zn\u00E1mo: \tanafylaktick\u00E9 reakce, toxick\u00E1 epiderm\u00E1ln\u00ED nekrol\u00FDza, nekrotizuj\u00EDc\u00ED angiitida (vaskulitida, ko\u017En\u00ED vaskulitida), reakce podobn\u00E9 ko\u017En\u00EDmu lupus erythematodes, reaktivace ko\u017En\u00EDho lupus erythematodes, fotosenzitivn\u00ED reakce, vyr\u00E1\u017Eka, kop\u0159ivka\nPoruchy svalov\u00E9 a kostern\u00ED soustavy a pojivov\u00E9 tk\u00E1n\u011B:\nNen\u00ED zn\u00E1mo: \tslabost, svalov\u00FD spasmus\nC\u00E9vn\u00ED poruchy:\nNen\u00ED zn\u00E1mo: \tpostur\u00E1ln\u00ED hypotenze\nCelkov\u00E9 poruchy a reakce v\u00A0m\u00EDst\u011B aplikace:\nNen\u00ED zn\u00E1mo: \thore\u010Dka\nPoruchy jater a \u017Elu\u010Dov\u00FDch cest\nNen\u00ED zn\u00E1mo: \t\u017Eloutenka (intrahepat\u00E1ln\u00ED cholestatick\u00E1 \u017Eloutenka)\nPsychiatrick\u00E9 poruchy:\nNen\u00ED zn\u00E1mo: \tdeprese, poruchy sp\u00E1nku\nNa d\u00E1vce z\u00E1visl\u00E9 ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky hydrochlorothiazidu (zejm\u00E9na poruchy elektrolyt\u016F) se mohou p\u0159i titraci hydrochlorothiazidu zvy\u0161ovat."@cs .