. . . "L\u00E9\u010Div\u00E1 l\u00E1tka\n\tEkvianalgetick\u00E9 d\u00E1vky (mg)\n\t\n\tParenter\u00E1ln\u011B (i.m.)\n\tPeror\u00E1ln\u011B\n\tMorfin\n\t10\n\t30-40\n\tHydromorfon\n\t1,5\n\t7,5\n\tOxykodon\n\t10-15\n\t20-30\n\tMethadon\n\t10\n\t20\n\tLevorfanol\n\t2\n\t4\n\tOxymorfin\n\t1\n\t10 (rekt\u00E1ln\u011B)\n\tDiamorfin\n\t5\n\t60\n\tPethidin\n\t75\n\t-\n\tKodein\n\t-\n\t200\n\tBuprenorfin\n\t0,4\n\t0,8 (sublingv\u00E1ln\u011B)\n\tKetobemidon\n\t10\n\t20-30\nTabulka 2: Doporu\u010Den\u00E1 \u00FAvodn\u00ED d\u00E1vka transderm\u00E1ln\u011B podan\u00E9ho fentanylu stanoven\u00E1 podle peror\u00E1ln\u00ED denn\u00ED d\u00E1vky morfinu ( u pacient\u016F, kte\u0159\u00ED vy\u017Eaduj\u00ED zm\u011Bnu opioidu)\n\tPeror\u00E1ln\u00ED d\u00E1vka morfinu (mg/24 h)\n\tTransderm\u00E1ln\u011B uvol\u0148ovan\u00FD fentanyl (mikrogramy/h)\n\t< 44\n\t12,5\n\t45 - 134\n\t25\n\t135-224\n\t50\n\t225-314\n\t75\n\t315-404\n\t100\n\t405-494\n\t125\n\t495-584\n\t150\n\t585-674\n\t175\n\t675-764\n\t200\n\t765-854\n\t225\n\t855-944\n\t250\n\t945-1034\n\t275\n\t1035-1124\n\t300\nTabulka 3: Doporu\u010Den\u00E1 \u00FAvodn\u00ED d\u00E1vka transderm\u00E1ln\u00EDho fentanylu stanoven\u00E1 podle peror\u00E1ln\u00ED denn\u00ED d\u00E1vky morfinu ( pro pacienty na stabiln\u00ED a dob\u0159e tolerovan\u00E9 opioidn\u00ED l\u00E9\u010Db\u011B )\n\tPeror\u00E1ln\u00ED d\u00E1vka morfinu (mg/24 h)\n\tTransderm\u00E1ln\u011B uvol\u0148ovan\u00FD fentanyl (mikrogramy/h)\n\t< 60\n\t12,5\n\t60-89\n\t25\n\t90-149\n\t50\n\t150-209\n\t75\n\t210-269\n\t100\n\t270-329\n\t125\n\t330-389\n\t150\n\t390-449\n\t175\n\t450-509\n\t200\n\t510-569\n\t225\n\t570-629\n\t250\n\t630-689\n\t275\n\t690-749\n\t300\nKombinac\u00ED n\u011Bkolika transderm\u00E1ln\u00EDch n\u00E1plast\u00ED lze doc\u00EDlit i\u00A0rychlosti uvol\u0148ov\u00E1n\u00ED fentanylu p\u0159evy\u0161uj\u00EDc\u00ED 100 mikrogram\u016F/h.\nPrvn\u00ED hodnocen\u00ED maxim\u00E1ln\u00EDho analgetick\u00E9ho \u00FA\u010Dinku p\u0159\u00EDpravku Fentanyl Orion by nem\u011Blo b\u00FDt provedeno d\u0159\u00EDve ne\u017E za 24 hodin po p\u0159ilo\u017Een\u00ED n\u00E1plasti."@cs . . . . . . "4174"^^ . . . . . . . . . "1"^^ . . . . . . . . "5607"^^ . . .