. . . "\u00DA\u010Dinnost risperidonu jako p\u0159\u00EDdatn\u00E9 l\u00E9\u010Dby k stabiliz\u00E1tor\u016Fm n\u00E1lady p\u0159i l\u00E9\u010Db\u011B akutn\u00ED m\u00E1nie byla \tdolo\u017Eena v jedn\u00E9 ze dvou 3t\u00FDdenn\u00EDch dvojit\u011B slep\u00FDch studi\u00ED u p\u0159ibli\u017En\u011B 300 pacient\u016F, kte\u0159\u00ED \tspl\u0148ovali DSM-IV krit\u00E9ria pro bipol\u00E1rn\u00ED poruchu I. V jedn\u00E9 3t\u00FDdenn\u00ED studii byl risperidon \tpod\u00E1v\u00E1n v d\u00E1vce 1 a\u017E 6 mg/den (po\u010D\u00E1te\u010Dn\u00ED d\u00E1vka 2 mg/den) spolu s lithiem nebo valpro\u00E1tem; \tkombinace s risperidonem byla \u00FA\u010Dinn\u011Bj\u0161\u00ED ne\u017E samotn\u00E9 lithium nebo valpro\u00E1t v\u00A0p\u0159edem \tstanoven\u00E9m v\u00FDstupu, tj. zm\u011Bn\u011B od v\u00FDchoz\u00EDho stavu v celkov\u00E9m YMRS sk\u00F3re ve 3. t\u00FDdnu."@cs . . . . . . "38286"^^ . "37751"^^ . "1"^^ .