<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-12> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-14> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasSectionTitle>	"4.5\tInterakce s\u00A0jin\u00FDmi l\u00E9\u010Div\u00FDmi p\u0159\u00EDpravky a jin\u00E9 formy interakce"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-7> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-9> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasText>	"Kombinace, kterou nejsou doporu\u010Dovan\u00E9:\nAlkohol::\nAkutn\u00ED intoxikace alkoholem je spojen\u00E1 se zv\u00FD\u0161en\u00FDm rizikem lakt\u00E1tov\u00E9 acid\u00F3zy, zvl\u00E1\u0161t\u011B v\u00A0p\u0159\u00EDpad\u011B hladov\u011Bn\u00ED nebo p\u0159i \u0161patn\u00E9 v\u00FD\u017Eiv\u011B a nedostate\u010Dnosti jater.\nVyvarujte se konzumace alkoholu a l\u00E9\u010Div\u00FDch p\u0159\u00EDpravk\u016F s\u00A0obsahem alkoholu.\nKontrastn\u00ED l\u00E1tky s\u00A0obsahem j\u00F3du:\nIntraven\u00F3zn\u00ED pod\u00E1n\u00ED kontrastn\u00EDch l\u00E1tek s\u00A0obsahem j\u00F3du m\u016F\u017Ee v\u00E9st k\u00A0selh\u00E1n\u00ED ledvin s\u00A0n\u00E1slednou kumulac\u00ED metforminu a zv\u00FD\u0161en\u00FDm rizikem lakt\u00E1tov\u00E9 acid\u00F3zy.\nU\u017E\u00EDv\u00E1n\u00ED metforminu mus\u00ED b\u00FDt p\u0159ed nebo v\u00A0dob\u011B vy\u0161et\u0159en\u00ED p\u0159eru\u0161eno a sm\u00ED b\u00FDt znovu obnoveno 48 hodin po vy\u0161et\u0159en\u00ED a to pouze pot\u00E9, co funkce ledvin byla op\u011Bt vyhodnocena jako norm\u00E1ln\u00ED (viz. bod 4.3 a 4.4). \nKombinace vy\u017Eaduj\u00EDc\u00ED zv\u00FD\u0161enou opatrnost:\nGlukokortikoidy (syst\u00E9mov\u00E9 a lok\u00E1ln\u00ED), beta-2-agonist\u00E9 a diuretika\nmaj\u00ED vlastn\u00ED hyperglykemickou aktivitu. Informujte pacienta a \u010Dast\u011Bji kontrolujte hladinu krevn\u00EDho cukru, zvl\u00E1\u0161t\u011B v \u00FAvodu l\u00E9\u010Dby. V\u00A0p\u0159\u00EDpad\u011B nutnosti upravte d\u00E1vkov\u00E1n\u00ED antidiabetick\u00E9ho l\u00E9ku b\u011Bhem l\u00E9\u010Dby s  jin\u00FDm l\u00E9\u010Div\u00FDm p\u0159\u00EDpravkem a p\u0159i jeho vysazen\u00ED.\nACE inhibitory\nmohou sn\u00ED\u017Eit hladinu cukru v\u00A0krvi. B\u011Bhem a po za\u0159azen\u00ED nebo vysazen\u00ED takov\u00E9ho l\u00E9\u010Div\u00E9ho p\u0159\u00EDpravku m\u016F\u017Ee b\u00FDt nutn\u00E9 upravit d\u00E1vkov\u00E1n\u00ED metforminu.\n"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-18> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-2> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-20> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC95492_doc-4-5-22> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://salt.semanticauthoring.org/ontologies/sdo#hasOrderNumber>	"004.005" .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://salt.semanticauthoring.org/ontologies/sdo#Section> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC95492_doc-4-5>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://linked.opendata.cz/ontology/spc/InteractionSection> .