. . "4.5 Interakce s\u00A0jin\u00FDmi l\u00E9\u010Div\u00FDmi p\u0159\u00EDpravky a jin\u00E9 formy interakce"@cs . "P\u0159i soub\u011B\u017En\u00E9 aplikaci cisplatiny a p\u0159\u00EDpravku Thioctacid 600 HR m\u016F\u017Ee b\u00FDt zeslaben \u00FA\u010Dinek cisplatiny.\nThioctacid 600 HR je chelata\u010Dn\u00EDm \u010Dinidlem. Z\u00E1sadn\u011B by se proto nem\u011Bl pod\u00E1vat sou\u010Dasn\u011B se slou\u010Deninami kov\u016F (nap\u0159. s\u00A0p\u0159\u00EDpravky obsahuj\u00EDc\u00EDmi \u017Eelezo, ho\u0159\u010D\u00EDk, a vzhledem k\u00A0obsahu v\u00E1pn\u00EDku ani s\u00A0ml\u00E9\u010Dn\u00FDmi v\u00FDrobky). U\u017E\u00EDv\u00E1-li se Thioctacid 600 HR 30 minut p\u0159ed sn\u00EDdan\u00ED, lze p\u0159\u00EDpravky s\u00A0obsahem \u017Eeleza \u010Di ho\u0159\u010D\u00EDku u\u017E\u00EDvat v\u00A0poledne nebo ve\u010Der. Proto\u017Ee m\u016F\u017Ee b\u00FDt zes\u00EDlen hypoglykemizuj\u00EDc\u00ED \u00FA\u010Dinek insulinu a peror\u00E1ln\u00EDch antidiabetik, doporu\u010Duje se, zejm\u00E9na v\u00A0po\u010D\u00E1te\u010Dn\u00EDm obdob\u00ED terapie p\u0159\u00EDpravkem Thioctacid 600 HR, prov\u00E1d\u011Bt pravideln\u00E9 kontroly glyk\u00E9mie. V\u00A0ojedin\u011Bl\u00FDch p\u0159\u00EDpadech m\u016F\u017Ee b\u00FDt zapot\u0159eb\u00ED sn\u00ED\u017Eit d\u00E1vku insulinu nebo peror\u00E1ln\u00EDch antidiabetik, aby se p\u0159ede\u0161lo projev\u016Fm hypoglyk\u00E9mie.\n"@cs . . . "004.005" .