<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-7> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://salt.semanticauthoring.org/ontologies/sdo#Section> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasSectionTitle>	"4.8 Ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasOrderNumber>	"004.008" .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-10> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-13> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-16> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-20> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasText>	"Stejn\u011B jako ostatn\u00ED lok\u00E1ln\u011B aplikovan\u00E9 l\u00E1tky pou\u017E\u00EDvan\u00E9 v oftalmologii, i timolol je absorbov\u00E1n do syst\u00E9mov\u00E9ho ob\u011Bhu. Proto m\u016F\u017Ee p\u016Fsobit podobn\u00E9 ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky, jako byly zaznamen\u00E1ny u syst\u00E9mov\u00FDch betablok\u00E1tor\u016F. Incidence syst\u00E9mov\u00FDch ne\u017E\u00E1douc\u00EDch \u00FA\u010Dink\u016F v souvislosti s lok\u00E1ln\u00EDm o\u010Dn\u00EDm pod\u00E1n\u00EDm je ni\u017E\u0161\u00ED ne\u017E u syst\u00E9mov\u00E9ho pod\u00E1n\u00ED. Mezi o\u010Dek\u00E1van\u00E9 ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky pat\u0159\u00ED ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky pozorovan\u00E9 u cel\u00E9 t\u0159\u00EDdy o\u010Dn\u00EDch betablok\u00E1tor\u016F.\nPoruchy imunitn\u00EDho syst\u00E9mu\n  Syst\u00E9mov\u00E9 alergick\u00E9 reakce, v\u010Detn\u011B angioed\u00E9mu, urtikarie, lokalizovan\u00E9ho nebo     \n  generalizovan\u00E9ho exant\u00E9mu, pruritu, anafylaktick\u00E9 reakce.\n\t  Poruchy metabolismu a v\u00FD\u017Eivy\n Hypoglykemie.\n\tPsychiatrick\u00E9 poruchy\nNespavost, deprese, no\u010Dn\u00ED m\u016Fry, ztr\u00E1ta pam\u011Bti.\n\t Poruchy nervov\u00E9ho syst\u00E9mu\nSynkopa, cerebrovaskul\u00E1rn\u00ED p\u0159\u00EDhoda, mozkov\u00E1 isch\u00E9mie, zv\u00FD\u0161en\u00FD v\u00FDskyt p\u0159\u00EDznak\u016F a zn\u00E1mek myastenie gravis, z\u00E1vrat\u011B, parest\u00E9zie, bolesti hlavy.\nPoruchy oka\nP\u0159\u00EDznaky a zn\u00E1mky podr\u00E1\u017Ed\u011Bn\u00ED o\u010D\u00ED: tj p\u00E1len\u00ED, p\u00EDch\u00E1n\u00ED, sv\u011Bd\u011Bn\u00ED, szen\u00ED, zarudnut\u00ED), blefaritida,\nkeratitida, neostr\u00E9 vid\u011Bn\u00ED, odchl\u00EDpen\u00ED chorioidey, po filtra\u010Dn\u00EDm z\u00E1kroku (viz bod 4.4), sn\u00ED\u017Een\u00E1 citlivost rohovky, pocit such\u00E9ho oka, korne\u00E1ln\u00ED eroze, ptoza,diplopie.\nSrde\u010Dn\u00ED poruchy \nBradykardie, bolest na hrudi, palpitace, otoky, arytmie, kongestivn\u00ED srde\u010Dn\u00ED selh\u00E1n\u00ED, atrioventrikul\u00E1rn\u00ED blok, srde\u010Dn\u00ED z\u00E1stava, srde\u010Dn\u00ED selh\u00E1n\u00ED.\nC\u00E9vn\u00ED poruchy \nHypotenze, Raynaud\u016Fv fenom\u00E9n, syndrom studen\u00FDch rukou a nohou.\n \nRespira\u010Dn\u00ED, hrudn\u00ED a mediastin\u00E1ln\u00ED poruch\nBronchospasmus (p\u0159edev\u0161\u00EDm u pacient\u016F s\u00A0preexistuj\u00EDc\u00ED bronchospastickou chorobou), du\u0161nost, ka\u0161el.\nGastrointestin\u00E1ln\u00ED poruchy\nDysgeuzie, nauzea, dyspepsie, pr\u016Fjem, sucho v \u00FAstech, bolest b\u0159icha, zvracen\u00ED.\nPoruchy k\u016F\u017Ee a podko\u017En\u00ED tk\u00E1n\u011B\nAlopecie, psoriaziformn\u00ED exant\u00E9m nebo exacerbace psori\u00E1zy, ko\u017En\u00ED vyr\u00E1\u017Eka.\t\n \nPoruchy svalov\u00E9 a kostern\u00ED soustavy a pojivov\u00E9 tk\u00E1n\u011B\nMyalgie.\n      \nPoruchy reproduk\u010Dn\u00EDho syst\u00E9mu a prsu\nSexu\u00E1ln\u00ED dysfunkce, sn\u00ED\u017Een\u00E9 libido.\nCelkov\u00E9 poruchy a reakce v m\u00EDst\u011B aplikace\nAstenie/\u00FAnava.\n"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-1> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-32> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-35> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-38> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-41> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-23> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-26> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-29> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC162005_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC162005_doc-4-8-3> .