"004.005" . . "4.5 Interakce s\u00A0jin\u00FDmi l\u00E9\u010Div\u00FDmi p\u0159\u00EDpravky a jin\u00E9 formy interakce"@cs . . . . . . "\u017D\u00E1dn\u00E9 specifick\u00E9 klinick\u00E9 studie zam\u011B\u0159en\u00E9 na interakce s l\u00E9\u010Divou l\u00E1tkou nebyly provedeny.\nExistuje mo\u017Enost vzniku aditivn\u00EDho \u00FA\u010Dinku vedouc\u00EDho k hypotenzi a/nebo k\u00A0v\u00FDrazn\u00E9 bradykardii v\u00A0p\u0159\u00EDpad\u011B sou\u010Dasn\u00E9ho pod\u00E1v\u00E1n\u00ED o\u010Dn\u00EDch betablok\u00E1tor\u016F a peror\u00E1ln\u00EDch blok\u00E1tor\u016F kalciov\u00FDch kan\u00E1l\u016F, beta blok\u00E1tor\u016F, antiarytmik (v\u010Detn\u011B amiodaronu), digitalisov\u00FDch glykosid\u016F, parasympatomimetik, guanethidinu.\n Byla hl\u00E1\u0161ena zes\u00EDlen\u00E1 beta blok\u00E1da (tj. sn\u00ED\u017Een\u00E1 tepov\u00E1 frekvence, myokardi\u00E1ln\u00ED deprese) p\u0159i sou\u010Dasn\u00E9 l\u00E9\u010Db\u011B CYP2D6 inhibitory (tj chinidin, fluoxetin, paroxetin) a timololu.\nP\u0159\u00EDle\u017Eitostn\u011B byly hl\u00E1\u0161eny p\u0159\u00EDpady mydri\u00E1zy, kdy\u017E byly o\u010Dn\u00ED betablok\u00E1tory pou\u017E\u00EDv\u00E1ny spolu s\u00A0adrenalinem.\n"@cs .