. . "4.8\tNe\u017E\u00E1douc\u00ED \u00FA\u010Dinky"@cs . "004.008" . "Nej\u010Dast\u011Bj\u0161\u00EDmi ne\u017E\u00E1douc\u00EDmi \u00FA\u010Dinky jsou pr\u016Fjem, svalov\u00E9 k\u0159e\u010De, \u00FAnava, nauzea, zvracen\u00ED a nespavost.\nNe\u017E\u00E1douc\u00ED \u00FA\u010Dinky hl\u00E1\u0161en\u00E9 ve v\u00EDce ne\u017E ojedin\u011Bl\u00FDch p\u0159\u00EDpadech jsou vyjmenov\u00E1ny v\u00A0tabulce n\u00ED\u017Ee a uvedeny podle t\u0159\u00EDd org\u00E1nov\u00FDch syst\u00E9m\u016F a \u010Detnosti. \u010Cetnosti jsou definovan\u00E9 jako: velmi \u010Dast\u00E9 (\u2265 1/10), \u010Dast\u00E9 (\u2265 1/100, < 1/10), m\u00E9n\u011B \u010Dast\u00E9 (\u2265 1/1000, < 1/100), vz\u00E1cn\u00E9 (\u22651/10 000, <1/1000), velmi vz\u00E1cn\u00E9 (<1/10000) a nen\u00ED zn\u00E1mo (z\u00A0dostupn\u00FDch \u00FAdaj\u016F nelze ur\u010Dit).\n\tT\u0159\u00EDdy org\u00E1nov\u00FDch syst\u00E9m\u016F\n\tVelmi \u010Dast\u00E9\n\t\u010Cast\u00E9\n\tM\u00E9n\u011B \u010Dast\u00E9\n\tVz\u00E1cn\u00E9\n\tInfekce a infestace\n\t\n\tNachlazen\u00ED\n\t\n\t\n\tPoruchy metabolismu a v\u00FD\u017Eivy\n\t\n\tAnorexie\n\t\n\t\n\tPsychiatrick\u00E9 poruchy\n\t\n\tHalucinace**,\nagitace**,\nagresivn\u00ED chov\u00E1n\u00ED**,\nabnorm\u00E1ln\u00ED sny a no\u010Dn\u00ED m\u016Fry **\n\t\n\t\n\tPoruchy nervov\u00E9ho syst\u00E9mu\n\t\n\tSynkopa*,\nz\u00E1vrat\u011B,\nnespavost\n\tZ\u00E1chvat*\n\tExtrapyramidov\u00E9 symptomy\n\tSrde\u010Dn\u00ED poruchy\n\t\n\t\n\tBradykardie\n\tSino-atri\u00E1ln\u00ED blok, \natrioventrikul\u00E1rn\u00ED blok\n\tGastrointestin\u00E1ln\u00ED poruchy\n\tPr\u016Fjem,\nnauzea\n\tZvracen\u00ED,\nb\u0159i\u0161n\u00ED dyskomfort\n\tGastrointestin\u00E1ln\u00ED krv\u00E1cen\u00ED,\n\u017Ealude\u010Dn\u00ED a duoden\u00E1ln\u00ED v\u0159edy\n\t\n\tPoruchy jater a \u017Elu\u010Dov\u00FDch cest\n\t\n\t\n\t\n\tJatern\u00ED dysfunkce v\u010Detn\u011B hepatitidy***\n\tPoruchy k\u016F\u017Ee a podko\u017En\u00ED tk\u00E1n\u011B\n\t\n\tVyr\u00E1\u017Eka,\npruritus\n\t\n\t\n\tPoruchy svalov\u00E9 a kostern\u00ED soustavy a pojivov\u00E9 tk\u00E1n\u011B\n\t\n\tSvalov\u00E9 k\u0159e\u010De\n\t\n\t\n\tPoruchy ledvin a mo\u010Dov\u00FDch cest\n\t\n\tMo\u010Dov\u00E1 inkontinence\n\t\n\t\n\tCelkov\u00E9 poruchy a reakce v m\u00EDst\u011B aplikace\n\tBolest hlavy\n\t\u00DAnava,\nbolest\n\t\n\t\n\tVy\u0161et\u0159en\u00ED\n\t\n\t\n\tM\u00EDrn\u00E9 zv\u00FD\u0161en\u00ED koncentrace svalov\u00E9 kreatinkin\u00E1zy v s\u00E9ru \n\t\n\tPoran\u011Bn\u00ED a otravy\n\t\n\t\u00DAraz\n\t\n\t\n*P\u0159i vy\u0161et\u0159ov\u00E1n\u00ED pacient\u016F s\u00A0podez\u0159en\u00EDm na synkopu nebo z\u00E1chvat je t\u0159eba vz\u00EDt v\u00A0\u00FAvahu srde\u010Dn\u00ED blok nebo dlouh\u00E9 sinusov\u00E9 pauzy (viz bod 4.4).\n**U hl\u00E1\u0161en\u00FDch halucinac\u00ED, abnorm\u00E1ln\u00EDch sn\u016F a no\u010Dn\u00EDch m\u016Fr, agitace a agresivn\u00EDho chov\u00E1n\u00ED do\u0161lo k\u00A0vymizen\u00ED t\u011Bchto p\u0159\u00EDznak\u016F po sn\u00ED\u017Een\u00ED d\u00E1vky nebo ukon\u010Den\u00ED l\u00E9\u010Dby.\n***V p\u0159\u00EDpad\u011B nevysv\u011Btliteln\u00E9 jatern\u00ED dysfunkce je t\u0159eba zv\u00E1\u017Eit vysazen\u00ED donepezilu.\n"@cs . . .