. . "4.1 Terapeutick\u00E9 indikace"@cs . . . . "004.001" . . . . . . . . . . . . . . . "Apo-Fluconazol je indikov\u00E1n pro n\u00E1sleduj\u00EDc\u00ED mykotick\u00E9 infekce (viz bod 5.1). \nApo-Fluconazol je indikov\u00E1n u dosp\u011Bl\u00FDch k l\u00E9\u010Db\u011B: \nKryptokokov\u00E9 meningitidy (viz bod 4.4). \nKokcidioidomyk\u00F3zy (viz bod 4.4). \nInvazivn\u00ED kandid\u00F3zy. \nSlizni\u010Dn\u00ED kandid\u00F3zy, v\u010Detn\u011B orofarynge\u00E1ln\u00ED, j\u00EDcnov\u00E9 kandid\u00F3zy, kandidurie a chronick\u00E9 mukokut\u00E1nn\u00ED kandid\u00F3zy. \nChronick\u00E9 or\u00E1ln\u00ED atrofick\u00E9 kandid\u00F3zy (z\u00E1n\u011Bty vznikl\u00E9 pod um\u011Bl\u00FDm chrupem), pokud dent\u00E1ln\u00ED hygiena nebo topick\u00E1 l\u00E9\u010Dba nen\u00ED dostate\u010Dn\u00E1. \nVagin\u00E1ln\u00ED kandid\u00F3zy akutn\u00ED \u010Di rekurentn\u00ED; pokud lok\u00E1ln\u00ED l\u00E9\u010Dba nen\u00ED dosta\u010Duj\u00EDc\u00ED. \nKandidov\u00E9 balanitidy, pokud lok\u00E1ln\u00ED l\u00E9\u010Dba nen\u00ED dosta\u010Duj\u00EDc\u00ED. \nDermatomyk\u00F3zy v\u010Detn\u011B tinea pedis, tinea corporis, tinea cruris, tinea versicolor, a ko\u017En\u00EDch kandidov\u00FDch infekc\u00ED, je-li indikov\u00E1na syst\u00E9mov\u00E1 l\u00E9\u010Dba. \nTinea unguinium (onychomyk\u00F3za) , pokud jin\u00E1 agens nejsou \u00FA\u010Dinn\u00E1 .\nApo-Fluconazol je indikov\u00E1n u dosp\u011Bl\u00FDch k profylaxi: \nRelapsu kryptokokov\u00E9 meningitidy u pacient\u016F s vysok\u00FDch rizikem rekurence. \nRelapsu orofarynge\u00E1ln\u00ED nebo j\u00EDcnov\u00E9 kandid\u00F3zy u pacient\u016F naka\u017Een\u00FDch HIV, u kter\u00FDch je vysok\u00E9 riziko relapsu. \nKe sn\u00ED\u017Een\u00ED v\u00FDskytu rekurentn\u00ED vagin\u00E1ln\u00ED kandid\u00F3zy (4 nebo v\u00EDce epizod ro\u010Dn\u011B). \nProfylaxe kandidov\u00FDch infekc\u00ED u pacient\u016F s dlouhodobou neutropeni\u00ED (jako jsou pacienti s hematologick\u00FDmi malignitami podstupuj\u00EDc\u00ED chemoterapii nebo transplantaci kmenov\u00FDch bun\u011Bk krvetvorby (viz bod 5.1)). \nApo-Fluconazol je indikov\u00E1n u novorozenc\u016F, kojenc\u016F, batolat, d\u011Bt\u00ED a mladistv\u00FDch ve v\u011Bku od 0 do 17 let: \nApo-Fluconazol se u\u017E\u00EDv\u00E1 k l\u00E9\u010Db\u011B slizni\u010Dn\u00ED kandid\u00F3zy (orofarynge\u00E1ln\u00ED, j\u00EDcnov\u00E9), invaz\u00EDvn\u00ED kandid\u00F3zy, kryptokokov\u00E9 meningitidy a k profylaxi kandidov\u00FDch infekc\u00ED u imunologicky oslaben\u00FDch pacient\u016F. Apo-Fluconazol se m\u016F\u017Ee u\u017E\u00EDvat jako udr\u017Eovac\u00ED l\u00E9\u010Dba k prevenci relapsu kryptokokov\u00E9 meningitidy u d\u011Bt\u00ED s vysok\u00FDm rizikem rekurence (viz bod 4.4). \nL\u00E9\u010Dbu je mo\u017En\u00E9 zah\u00E1jit je\u0161t\u011B p\u0159ed obdr\u017Een\u00EDm v\u00FDsledk\u016F kultiva\u010Dn\u00EDho nebo jin\u00E9ho laboratorn\u00EDho vy\u0161et\u0159en\u00ED, ale jakmile jsou v\u00FDsledky t\u011Bchto vy\u0161et\u0159en\u00ED dostupn\u00E9, je t\u0159eba podle nich antiinfek\u010Dn\u00ED l\u00E9\u010Dbu upravit. \nJe nutn\u00E9 br\u00E1t v \u00FAvahu ofici\u00E1ln\u00ED doporu\u010Den\u00ED pro spr\u00E1vn\u00E9 pou\u017Eit\u00ED antimykotik.\n"@cs .