<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-2> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-4> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-5> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-6> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasOrderNumber>	"004.008" .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasSectionTitle>	"4.8  \tNe\u017E\u00E1douc\u00ED \u00FA\u010Dinky"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasText>	"Metoprolol je dob\u0159e tolerov\u00E1n a ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky jsou obecn\u011B m\u00EDrn\u00E9 a reverzibiln\u00ED.\nV n\u00E1sleduj\u00EDc\u00ED tabulce jsou shrnuty ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky metoprololu rozd\u011Blen\u00E9 do skupin podle terminologie MedDRA s uveden\u00EDm frekvence v\u00FDskytu: velmi \u010Dast\u00E9 (>=1/10); \u010Dast\u00E9 (>=1/100 a\u017E <1/10); m\u00E9n\u011B \u010Dast\u00E9 (>=1/1000 a\u017E <1/100); vz\u00E1cn\u00E9 (>=1/10000 a\u017E <1/1000); velmi vz\u00E1cn\u00E9 (<1/10000), nen\u00ED zn\u00E1mo (z dostupn\u00FDch \u00FAdaj\u016F nelze ur\u010Dit):\nPoruchy metabolismu a v\u00FD\u017Eivy \uFFFD Vz\u00E1cn\u00E9: maskov\u00E1n\u00ED p\u0159\u00EDznak\u016F hypoglyk\u00E9mie.\nPsychiatrick\u00E9 poruchy \uFFFD \u010Cast\u00E9: poruchy sp\u00E1nku.\uFFFDM\u00E9n\u011B \u010Dast\u00E9: d\u011Bsiv\u00E9 sny.\nPoruchy nervov\u00E9ho syst\u00E9mu \uFFFD M\u00E9n\u011B \u010Dast\u00E9: z\u00E1vrat\u011B.\uFFFDVz\u00E1cn\u00E9: parestezie.\nPoruchy oka \uFFFD Velmi vz\u00E1cn\u00E9: poruchy zraku, suchost spojivek.\nPoruchy ucha a labyrintu \uFFFD Velmi vz\u00E1cn\u00E9: tinitus.\nSrde\u010Dn\u00ED poruchy \uFFFD M\u00E9n\u011B \u010Dast\u00E9: bradykardie.\uFFFDVz\u00E1cn\u00E9: palpitace, zhor\u0161en\u00ED kardi\u00E1ln\u00ED dekompenzace, arytmie.\nC\u00E9vn\u00ED poruchy \uFFFD Vz\u00E1cn\u00E9: ortostatick\u00E1 hypotenze, Raynaud\u016Fv syndrom.\uFFFDVelmi vz\u00E1cn\u00E9: klaudikace.\nRespira\u010Dn\u00ED, hrudn\u00ED a mediastin\u00E1ln\u00ED poruchy \uFFFD M\u00E9n\u011B \u010Dast\u00E9: n\u00E1mahov\u00E1 du\u0161nost.\uFFFDVz\u00E1cn\u00E9: bronchospasmus.\nGastrointestin\u00E1ln\u00ED poruchy \uFFFD \u010Cast\u00E9: nauzea, zvracen\u00ED.\uFFFDVz\u00E1cn\u00E9: pr\u016Fjem, dyspepsie.\uFFFDVelmi vz\u00E1cn\u00E9: sucho v \u00FAstech.\nPoruchy k\u016F\u017Ee a podko\u017En\u00ED tk\u00E1n\u011B \uFFFD Vz\u00E1cn\u00E9: alergick\u00E9 ko\u017En\u00ED projevy jako nap\u0159. kop\u0159ivkov\u00FD ekz\u00E9m nebo psoriatiformn\u00ED vyr\u00E1\u017Eka.\uFFFDVelmi vz\u00E1cn\u00E9: alopecie, zv\u00FD\u0161en\u00E9 pocen\u00ED.\nPoruchy svalov\u00E9 a kostern\u00ED soustavy a pojivov\u00E9 tk\u00E1n\u011B \uFFFD Vz\u00E1cn\u00E9: k\u0159e\u010De.\nPoruchy reproduk\u010Dn\u00EDho syst\u00E9mu a prsu \uFFFD Vz\u00E1cn\u00E9: impotence.\nCelkov\u00E9 poruchy a reakce v m\u00EDst\u011B aplikace \uFFFD Velmi \u010Dast\u00E9: \u00FAnava.\uFFFDVz\u00E1cn\u00E9: ed\u00E9my.\nVy\u0161et\u0159en\u00ED \uFFFD Vz\u00E1cn\u00E9: m\u00EDrn\u00E9 zv\u00FD\u0161en\u00ED hladiny triglycerid\u016F, m\u00EDrn\u00E9 zv\u00FD\u0161en\u00ED hladiny cholesterolu.\n"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-13> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-14> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-15> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-16> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-1> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-10> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-11> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-12> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-7> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-8> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://salt.semanticauthoring.org/ontologies/sdo#hasParagraph>	<http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC141315_doc-4-8-9> .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC141315_doc-4-8>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://salt.semanticauthoring.org/ontologies/sdo#Section> .