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<http://linked.opendata.cz/resource/sukl/spc/section/SPC115612_doc-5-3>	<http://salt.semanticauthoring.org/ontologies/sdo#hasText>	"Neklinick\u00E9 \u00FAdaje z\u00EDskan\u00E9 na z\u00E1klad\u011B konven\u010Dn\u00EDch farmakologick\u00FDch studi\u00ED bezpe\u010Dnosti, toxicity po jednor\u00E1zov\u00E9m a opakovan\u00E9m pod\u00E1v\u00E1n\u00ED a genotoxicity neodhalily \u017E\u00E1dn\u00E9 zvl\u00E1\u0161tn\u00ED riziko pro \u010Dlov\u011Bka. \nV\u00FDsledky  reproduk\u010Dn\u00EDch studi\u00ED proveden\u00FDch u kr\u00E1l\u00EDk\u016F a potkan\u016F neprok\u00E1zaly teratogenn\u00ED \u00FA\u010Dinek, ale prok\u00E1zaly embryo/fetotoxick\u00E9 \u00FA\u010Dinky p\u0159i z\u00FD\u0161en\u00E9 resorpci, men\u0161\u00ED velikost ml\u00E1\u010Fat a sn\u00ED\u017Een\u00ED porodn\u00ED hmotnosti, a d\u00E1le m\u00EDrn\u00E9 prodlou\u017Een\u00ED doby osifikace v d\u00E1vk\u00E1ch toxick\u00FDch pro matku. Studie karcinogenity pyridostigmin-bromidu nebyly provedeny.\n"@cs .
<http://linked.opendata.cz/resource/sukl/spc/section/SPC115612_doc-5-3>	<http://salt.semanticauthoring.org/ontologies/sdo#hasSectionTitle>	"5.3. P\u0159edklinick\u00E9 \u00FAdaje vztahuj\u00EDc\u00ED se k bezpe\u010Dnosti "@cs .
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